Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9279307 | 0.91 | HPGD (0.39) | ESRRALMNANCEH1NPSR1RAB9A | |
| SCHEMBL1416301 | 0.82 | LMNA (0.41) | ESRRALMNANCEH1PTK2BRAB9A | |
| SCHEMBL398680 | 0.80 | MEN1 (0.42) | LMNANCEH1NPSR1RAB9AL3MBTL1 | |
| SCHEMBL5706038 | 0.79 | KMT2A (0.57) | ESRRARAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL11602981 | 0.78 | PTK2B (0.44) | LMNAPTK2BNPSR1RAB9AMEN1 | |
| SCHEMBL29450644 | 0.78 | PTK2B (0.51) | LMNAPTK2BRAB9AMEN1KMT2A | |
| SCHEMBL56863 | 0.78 | PTK2B (0.51) | LMNAPTK2BRAB9AMEN1KMT2A | |
| SCHEMBL8370151 | 0.75 | TSPO (0.37) | LMNANPSR1MEN1KMT2AHTT | |
| SCHEMBL8060132 | 0.74 | ALDH1A1 (0.52) | NPSR1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL11311995 | 0.74 | ALDH1A1 (0.49) | ESRRALMNANCEH1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001036524-A1 | POLYCARBONATE COMPOSITIONS WITH IMPROVED PROCESSABILITY | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2001-05-25 | — | — | WO | disclosed |