SCHEMBL398680

SCHEMBL398680

O=C(O)Oc1c(Cl)c(Cl)cc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
KDM4E B2RXH2 4/20 0.42
HPGD P15428 4/20 0.42
ALDH1A1 P00352 3/20 0.42
CYP1A2 P05177 3/20 0.42
HSD17B10 Q99714 2/20 0.42
CYP2C19 P33261 2/20 0.42
GLA P06280 1/20 0.42
LMNA P02545 4/20 0.38
NCEH1 Q6PIU2 1/20 0.38
MAPT P10636 3/20 0.37
HTT P42858 2/20 0.37
GPR84 Q9NQS5 1/20 0.37
PKM P14618 1/20 0.37
CYP2A6 P11509 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
ERN1 O75460 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
NPC1 O15118 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9279307 0.88 HPGD (0.39) MEN1KMT2AKDM4EHPGDALDH1A1
SCHEMBL8370153 0.83 TSPO (0.41) MEN1KMT2AKDM4EHPGDALDH1A1
SCHEMBL27556715 0.83 MEN1 (0.42) MEN1KMT2AKDM4EHPGDALDH1A1
SCHEMBL3999298 0.82 ALDH1A1 (0.55) MEN1KMT2AKDM4EHPGDALDH1A1
SCHEMBL7941266 0.80 ESRRA (0.37) MEN1KMT2AHPGDALDH1A1HSD17B10
SCHEMBL8153278 0.79 CYP2A6 (0.47) MEN1KMT2AKDM4EHPGDALDH1A1
SCHEMBL29243294 0.75 GPR84 (0.46) MEN1KMT2AKDM4EHPGDALDH1A1
SCHEMBL10771028 0.74 KMT2A (0.66) MEN1KMT2AKDM4EHPGDALDH1A1
SCHEMBL27556714 0.73 CYP1A2 (0.42) MEN1KMT2AKDM4EALDH1A1CYP1A2
SCHEMBL10352802 0.71 KDM4E (0.42) MEN1KMT2AKDM4EHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240084109-A1 THERMOPLASTIC PULVERULENT COMPOSITION FOR THREE-DIMENSIONAL PRINTING BASF SE (DE) 2024-03-14 US disclosed
EP-4271550-A1 THERMOPLASTIC PULVERULENT COMPOSITION FOR THREE-DIMENSIONAL PRINTING BASF SE (DE) 2023-11-08 EP disclosed
EP-4247618-A1 FLAME-RETARDANT PULVERULENT COMPOSITION AND 3D-PRINTED OBJECT OBTAINED FROM THE SAME BASF SE (DE) 2023-09-27 EP disclosed
WO-2022144160-A1 THERMOPLASTIC PULVERULENT COMPOSITION FOR THREE-DIMENSIONAL PRINTING BASF SE (DE) 2022-07-07 WO disclosed
WO-2022106402-A1 FLAME-RETARDANT PULVERULENT COMPOSITION AND 3D-PRINTED OBJECT OBTAINED FROM THE SAME BASF SE (DE) 2022-05-27 WO disclosed
CN-107278219-B Deoxybenzoin-containing flame-retardant polymer composition 巴斯夫欧洲公司 2021-03-05 CN disclosed
EP-2825589-B1 NOR-HALS COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2020-05-06 EP disclosed
US-10414985-B2 Heptaphosphorus-derived compounds as flame retardants BASF SE (DE) 2019-09-17 US disclosed
US-10316169-B2 NOR-HALS compounds as flame retardants BASF SE (DE) 2019-06-11 US disclosed
US-20180216008-A1 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2018-08-02 US disclosed
EP-1987094-A1 AROMATIC PHOSPHATE ACID ESTER FLAME RETARDANT COMPOSITIONS Ciba Holding Inc. (CH) 2008-11-05 EP disclosed
EP-1984440-A1 AROMATIC SULPHONATE FLAME RETARDANT COMPOSITIONS Ciba Holding Inc. (CH) 2008-10-29 EP disclosed
WO-2008119693-A1 DOPO FLAME RETARDANT COMPOSITIONS BASF SE (CH) 2008-10-09 WO disclosed
EP-1915427-A1 POLYCARBONATE FLAME RETARDENT COMPOSITIONS Ciba Specialty Chemicals Holding Inc. (CH) 2008-04-30 EP disclosed
WO-2007096260-A1 AROMATIC PHOSPHATE ACID ESTER FLAME RETARDANT COMPOSITIONS CIBA HOLDING INC. (CH) 2007-08-30 WO disclosed
WO-2007093513-A1 AROMATIC SULPHONATE FLAME RETARDANT COMPOSITIONS CIBA HOLDING INC. (CH) 2007-08-23 WO disclosed
WO-2007020211-A1 POLYCARBONATE FLAME RETARDENT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-02-22 WO disclosed
US-5191036-A Polycarbonate, aromatic polyestersiloxane block polymer, impact strength MITSUBISHI RAYON CO., LTD. (JP) 1993-03-02 US disclosed
US-5084527-A Polyestersiloxane copolymers for impact strength MITSUBISHI RAYON CO., LTD. (JP) 1992-01-28 US disclosed
EP-0384460-A1 Thermoplastic resin composition MITSUBISHI RAYON CO., LTD (JP) 1990-08-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180216008-A1 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS PFAS, PCBP1, DDT MEN1 3373/4885KMT2A 1171/4885KDM4E 1196/4885
US-10414985-B2 Heptaphosphorus-derived compounds as flame retardants PFAS, PCBP1, DDT MEN1 1640/4885KMT2A 1058/4885KDM4E 1397/4885
US-10316169-B2 NOR-HALS compounds as flame retardants PFAS, NONO, PARG MEN1 4290/4885KMT2A 1032/4885KDM4E 982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.