SCHEMBL794230

SCHEMBL794230

Brc1cn2ccccc2n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 14/20 0.58
NPC1 O15118 13/20 0.58
KDM4E B2RXH2 8/20 0.58
POLB P06746 2/20 0.58
SMN1; SMN2 Q16637 5/20 0.56
ALOX12 P18054 1/20 0.56
NFKB1 P19838 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
PTGS1 P23219 1/20 0.52
PTGS2 P35354 1/20 0.52
GFER P55789 2/20 0.47
MAPT P10636 4/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
ALDH1A1 P00352 4/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
PKM P14618 2/20 0.45
EPHX2 P34913 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31731985 0.77 RAB9A (0.67) RAB9ANPC1KDM4EPOLBSMN1; SMN2
SCHEMBL29372978 0.76 RAB9A (0.59) RAB9ANPC1KDM4EPOLBSMN1; SMN2
SCHEMBL3313092 0.76 RAB9A (0.65) RAB9ANPC1KDM4EPOLBSMN1; SMN2
SCHEMBL2079932 0.76 PTGS1 (0.58) RAB9ANPC1KDM4EPOLBSMN1; SMN2
SCHEMBL13218389 0.74 PTGS1 (0.52) RAB9ANPC1KDM4EPOLBSMN1; SMN2
SCHEMBL171008 0.74 PTGS1 (0.52) RAB9ANPC1KDM4EPOLBSMN1; SMN2
SCHEMBL2482387 0.74 PTGS1 (0.52) RAB9ANPC1KDM4EPOLBSMN1; SMN2
SCHEMBL20893047 0.74 PTGS1 (0.52) RAB9ANPC1KDM4EPOLBSMN1; SMN2
SCHEMBL1723055 0.74 PTGS1 (0.52) RAB9ANPC1KDM4EPOLBSMN1; SMN2
SCHEMBL755953 0.74 RAB9A (0.58) RAB9ANPC1KDM4EPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636385-B2 Selective ligands for tau aggregates SENTONIX, INC. (US) 2026-05-26 US disclosed
EP-4741392-A1 1H-PYRAZOLO[4,3-C]PYRIDINE COMPOUND, AND COMPOSITION THEREOF AND USE THEREOF Shenzhen TargetRx Co., Ltd. (CN) 2026-05-13 EP disclosed
US-20250388577-A1 METTL3 INHIBITORY COMPOUNDS STORM THERAPEUTICS LTD (GB) 2025-12-25 US disclosed
US-20250333399-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES KHORA SPV 1 LLC (US) 2025-10-30 US disclosed
US-12358915-B2 METTL3 inhibitory compounds STORM Therapeutics Ltd. (GB) 2025-07-15 US disclosed
US-12331039-B2 Inhibitors of fibroblast growth factor receptor kinases KHORA SPV 1, LLC (US) 2025-06-17 US disclosed
CN-119954831-A Pyrimidopyrazoles, preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2025-05-09 CN disclosed
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 US disclosed
US-20250115569-A1 SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS LARIO THERAPEUTICS LTD (GB) 2025-04-10 US disclosed
CN-119707953-A Thiadiazolidinone derivative, and preparation method and application thereof 中国药科大学 2025-03-28 CN disclosed
WO-2008078091-A1 BICYCLIC HETEROCYCLIC COMPOUNDS AS FGFR INHIBITORS ASTEX THERAPEUTICS LIMITED (GB) 2008-07-03 WO disclosed
US-6358885-B1 PREEMERGENT OR POSTEMERGENT HERBICIDES OR PLANT GROWTH REGULANTS MISSISSIPPI STATE UNIVERSITY 2002-03-19 US disclosed
US-5977028-A Substituted phenylheterocyclic herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-11-02 US disclosed
EP-0626962-B1 SUBSTITUTED PHENYLHETEROCYCLIC HERBICIDES DU PONT (US) 1999-03-17 EP disclosed
US-5670455-A Substituted phenylheterocyclic herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-09-23 US disclosed
EP-0626962-A1 SUBSTITUTED PHENYLHETEROCYCLIC HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-12-07 EP disclosed
EP-0238070-B1 Sulfonylurea compounds, their production and herbicidal use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-29 EP disclosed
WO-1993015074-A1 SUBSTITUTED PHENYLHETEROCYCLIC HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-08-05 WO disclosed
US-5017212-A For rice paddies TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-05-21 US disclosed
EP-0238070-A2 Sulfonylurea compounds, their production and herbicidal use Takeda Chemical Industries, Ltd. (JP) 1987-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12358915-B2 METTL3 inhibitory compounds METTL3, METTL16, DIMT1 RAB9A 1839/4885NPC1 2030/4885KDM4E 62/4885
US-12636385-B2 Selective ligands for tau aggregates MAPT, PSEN2, PSEN1 RAB9A 1472/4885NPC1 242/4885KDM4E 4519/4885
US-12331039-B2 Inhibitors of fibroblast growth factor receptor kinases FGFR1, FGFR2, FGFR3 RAB9A 2047/4885NPC1 1043/4885KDM4E 2742/4885
US-20250115569-A1 SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS CACNA1A, CACNA1E, CACNA1S RAB9A 417/4885NPC1 3262/4885KDM4E 2441/4885
US-20250333399-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES FGFR1, FGFR2, FGFR3 RAB9A 2047/4885NPC1 1043/4885KDM4E 2742/4885
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS RAB9A 583/4885NPC1 2316/4885KDM4E 2083/4885
US-20250388577-A1 METTL3 INHIBITORY COMPOUNDS METTL3, RNMT, TPMT RAB9A 1986/4885NPC1 418/4885KDM4E 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.