SCHEMBL755953

SCHEMBL755953

Clc1cn2ccccc2n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 13/20 0.58
NPC1 O15118 12/20 0.58
PTGS1 P23219 1/20 0.52
PTGS2 P35354 1/20 0.52
SMN1; SMN2 Q16637 4/20 0.50
MAPT P10636 3/20 0.50
KDM4E B2RXH2 8/20 0.49
POLB P06746 2/20 0.49
GFER P55789 2/20 0.47
ALOX12 P18054 1/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
PKM P14618 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
ALDH1A1 P00352 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
EPHX2 P34913 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31731985 0.77 RAB9A (0.67) RAB9ANPC1PTGS1PTGS2SMN1; SMN2
SCHEMBL2079932 0.76 PTGS1 (0.58) RAB9ANPC1PTGS1PTGS2SMN1; SMN2
SCHEMBL3313092 0.76 RAB9A (0.65) RAB9ANPC1PTGS1PTGS2SMN1; SMN2
SCHEMBL13218389 0.74 PTGS1 (0.52) RAB9ANPC1PTGS1PTGS2SMN1; SMN2
SCHEMBL20893047 0.74 PTGS1 (0.52) RAB9ANPC1PTGS1PTGS2SMN1; SMN2
SCHEMBL794230 0.74 RAB9A (0.58) RAB9ANPC1PTGS1PTGS2SMN1; SMN2
SCHEMBL295906 0.74 PIK3CG (0.52) RAB9ANPC1PTGS1PTGS2SMN1; SMN2
SCHEMBL2482387 0.74 PTGS1 (0.52) RAB9ANPC1PTGS1PTGS2SMN1; SMN2
SCHEMBL171008 0.74 PTGS1 (0.52) RAB9ANPC1PTGS1PTGS2SMN1; SMN2
SCHEMBL1723055 0.74 PTGS1 (0.52) RAB9ANPC1PTGS1PTGS2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10338692-A None JP disclosed
EP-3983411-B1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD (IN) 2026-05-27 EP disclosed
US-12384787-B2 Fused heterocyclic compounds and their use as pest control agents PI INDUSTRIES LTD (IN) 2025-08-12 US disclosed
US-12336981-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. (US) 2025-06-24 US disclosed
CN-114008043-B Condensed heterocyclic compounds and their use as pest control agents PI工业有限公司 2024-06-07 CN disclosed
US-20230346753-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT VALO HEALTH, INC. 2023-11-02 US disclosed
US-11787789-B2 Compound for an organic electric element, an organic electric element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2023-10-17 US disclosed
US-11787789-B2 Compound for an organic electric element, an organic electric element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2023-10-17 US disclosed
US-11547701-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. (US) 2023-01-10 US disclosed
US-20220251094-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD. (IN) 2022-08-11 US disclosed
WO-1997027205-A1 IMIDAZO[1,2-A]PYRIDINE C-NUCLEOSIDES AS ANTIVIRAL AGENTS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1997-07-31 WO disclosed
WO-1997011075-A1 TRIAZOLE COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-03-27 WO disclosed
EP-0305939-B1 Process of producing sulfonylurea derivatives TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1994-11-02 EP disclosed
EP-0238070-B1 Sulfonylurea compounds, their production and herbicidal use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-29 EP disclosed
US-5270322-A Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them DR. KARL THOMAE GMBH (DE) 1993-12-14 US disclosed
US-5017212-A For rice paddies TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-05-21 US disclosed
US-4994571-A Reacting heterocycle-containing sulfonamide compound with carbonyl compound TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-02-19 US disclosed
EP-0383319-A2 Imidazopyridines, their production and use Takeda Chemical Industries, Ltd. (JP) 1990-08-22 EP disclosed
EP-0305939-A1 Process of producing sulfonylurea derivatives Takeda Chemical Industries, Ltd. (JP) 1989-03-08 EP disclosed
EP-0238070-A2 Sulfonylurea compounds, their production and herbicidal use Takeda Chemical Industries, Ltd. (JP) 1987-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11787789-B2 Compound for an organic electric element, an organic electric element using the same, and an electronic device thereof PIEZO1, ORAI2, OCIAD1 RAB9A 3826/4885NPC1 2726/4885PTGS1 2449/4885
US-12384787-B2 Fused heterocyclic compounds and their use as pest control agents DDT, ACHE, KEAP1 RAB9A 29/4885NPC1 3338/4885PTGS1 1070/4885
US-12336981-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNMT, NNT RAB9A 1657/4885NPC1 161/4885PTGS1 1930/4885
US-11547701-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNMT, NQO1 RAB9A 1917/4885NPC1 174/4885PTGS1 1975/4885
US-20220251094-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS DDT, ACHE, KEAP1 RAB9A 29/4885NPC1 3338/4885PTGS1 1070/4885
US-20230346753-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT NAMPT, NNMT, NQO1 RAB9A 1445/4885NPC1 123/4885PTGS1 1980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.