Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23254021 | 0.72 | PDK2 (0.47) | PSMB5PDK2PDK4CHRNB2CHRNA4 | |
| SCHEMBL19067631 | 0.69 | PDK2 (0.34) | PDK2PDK4KDM4EUSP2HPGD | |
| SCHEMBL22165239 | 0.69 | PSMB5 (0.37) | PSMB5 | |
| SCHEMBL26841823 | 0.69 | KDM4E (0.37) | KDM4EHPGD | |
| SCHEMBL24574591 | 0.68 | PSMB5 (0.35) | PSMB5PDK2PDK4 | |
| SCHEMBL7940997 | 0.68 | CHRNA7 (0.36) | PDK2PDK4 | |
| SCHEMBL10200506 | 0.66 | JAK3 (0.35) | KDM4EHPGDNPSR1HSD17B10 | |
| SCHEMBL9209136 | 0.66 | NOS3 (0.32) | — | |
| SCHEMBL9209139 | 0.66 | NCF1 (0.41) | KDM4EHSD17B10 | |
| SCHEMBL26709437 | 0.66 | LMNA (0.39) | KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054278-A2 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2010-05-14 | — | — | WO | disclosed |