Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSF1 | Q00613 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 10/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943995 | 0.91 | HSF1 (0.36) | HSF1ADORA1ADORA2AADORA3LYN | |
| SCHEMBL7937747 | 0.90 | HSF1 (0.35) | HSF1ADORA1ADORA2AADORA3LYN | |
| SCHEMBL7937752 | 0.83 | ADORA2A (0.39) | HSF1ADORA1ADORA2AADORA3LYN | |
| SCHEMBL7944078 | 0.82 | PDE4B (0.42) | HSF1ADORA1ADORA2AADORA3ADORA2B | |
| SCHEMBL7946794 | 0.77 | ADORA1 (0.39) | HSF1ADORA1ADORA2AADORA3LYN | |
| SCHEMBL7944114 | 0.76 | PDE4B (0.48) | HSF1ADORA1ADORA2AADORA3HPGD | |
| SCHEMBL7937864 | 0.75 | ADORA2A (0.38) | ADORA1ADORA2AADORA3LYNHPGD | |
| SCHEMBL7945987 | 0.72 | TYRO3 (0.36) | HSF1HPGD | |
| SCHEMBL7947184 | 0.71 | CYP1A2 (0.45) | HPGD | |
| SCHEMBL7944000 | 0.71 | ALDH1A1 (0.33) | ADORA1ADORA2AADORA3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008775-A1 | AMINOPYRIDOPYRAZINONE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |