SCHEMBL7944172

SCHEMBL7944172

Cl[Hf](Cl)(=C(c1ccccc1)c1ccccc1)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HTR6 P50406 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL818471 0.79 HTR6 (0.33) HTR6HTR2A
SCHEMBL6280683 0.74 ATM (0.38) ATMMEN1KMT2A
SCHEMBL8856012 0.74 LMNA (0.35) KMT2A
SCHEMBL3383074 0.74 HTR6 (0.33) HTR6HTR2A
SCHEMBL7951352 0.73 HTR2A (0.35) HTR6HTR2A
SCHEMBL215792 0.73 HTR2A (0.35) HTR6HTR2A
SCHEMBL3383168 0.73 HTR2A (0.35) MEN1KMT2AHTR6HTR2A
SCHEMBL216950 0.72 HTR6 (0.33) HTR6HTR2A
SCHEMBL5853982 0.72 MEN1 (0.33) ATMMEN1KMT2A
SCHEMBL6917975 0.71 HTR6 (0.32) HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8969482-B2 Dynamic modulation of metallocene catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-03-03 US claimed
EP-2760895-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS Exxon-Mobil Chemical Patents Inc. (US) 2014-08-06 EP claimed
US-20130085232-A1 Dynamic Modulation of Metallocene Catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-04 US claimed
WO-2013048848-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-04 WO claimed
US-9919300-B2 1-hexene production process SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-03-20 US disclosed
EP-2484685-B1 TRANSITION METAL COMPLEX, PREPARATION METHOD FOR SAID TRANSITION METAL COMPLEX, TRIMERIZATION CATALYST, PREPARATION METHOD FOR 1-HEXENE, PREPARATION METHOD FOR ETHYLENE POLYMER, SUBSTITUTED CYCLOPENTADIENE COMPOUND, AND PREPARATION METHOD FOR SAID SUBSTITUTED CYCLOPENTADIENE COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-11-01 EP disclosed
US-20170036200-A1 1-HEXENE PRODUCTION PROCESS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-09 US disclosed
US-20150105572-A1 TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-04-16 US disclosed
US-20150105237-A1 CATALYTIC COMPONENT FOR TRIMERIZATION AND TRIMERIZATION CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-04-16 US disclosed
US-8969482-B2 Dynamic modulation of metallocene catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-03-03 US disclosed
EP-2760895-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS Exxon-Mobil Chemical Patents Inc. (US) 2014-08-06 EP disclosed
WO-2013048848-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-04 WO disclosed
US-6313240-B1 ETHYLENE IS COPOLYMERIZED WITH AN .ALPHA.-OLEFIN HAVING THREE OR MORE CARBONS BY USE OF AN OLEFIN POLYMERIZATION CATALYST COMPRISING HAFNIUM METALLOCENE COMPOUND, IONIZING COMPOUND, OGRANOALUMINUM COMPOUND TOSOH CORPORATION (JP) 2001-11-06 US disclosed
US-5817590-A METALLOCENE, IONIZING IONIC COMPOUND, ORGANOALUMINUM COMPOUND, LEWIS BASE TOSOH CORPORATION (JP) 1998-10-06 US disclosed
EP-0612768-B1 Process for producing ethylene/alpha-olefin copolymer TOSOH CORP (JP) 1997-11-12 EP disclosed
EP-0648786-B1 Process for producing alpha-olefin polymer TOSOH CORP (JP) 1997-07-16 EP disclosed
US-5576259-A POLYMERIZATION CATALYST INCLUDING METALLOCENE COMPOUND, IONIC COMPOUND, ORGANOALUMINUM COMPOUND, AND LEWIS BASE TOSOH CORPORATION (JP) 1996-11-19 US disclosed
EP-0708117-A1 Process for producing copolymer rubber SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-04-24 EP disclosed
EP-0648786-A1 Process for producing alpha-olefin polymer Tosoh Corporation (JP) 1995-04-19 EP disclosed
EP-0612768-A1 Process for producing ethylene/alpha-olefin copolymer TOSOH CORPORATION (JP) 1994-08-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170036200-A1 1-HEXENE PRODUCTION PROCESS AP1M1, HK1, CYC1 ATM 2987/4885MEN1 587/4885KMT2A 3719/4885
US-20150105572-A1 TRANSITION METAL COMPLEX AP1M1, AP3M1, EMC1 ATM 2572/4885MEN1 163/4885KMT2A 3193/4885
US-20150105237-A1 CATALYTIC COMPONENT FOR TRIMERIZATION AND TRIMERIZATION CATALYST AP1M1, AMY1A, AP3M1 ATM 2953/4885MEN1 917/4885KMT2A 4503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.