Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30597995 | 1.00 | TSHR (0.57) | TSHRCYP3A4CYP2C9CYP2C19PLA2G1B | |
| Hydrochloric Acid SCHEMBL3395744 | 0.98 | TSHR (0.56) | TSHRCYP3A4CYP2C9CYP2C19PLA2G1B | |
| SCHEMBL28294737 | 0.86 | PLA2G1B (0.59) | TSHRCYP3A4CYP2C9CYP2C19PLA2G1B | |
| SCHEMBL11526512 | 0.85 | CYP3A4 (0.62) | TSHRCYP3A4CYP2C9CYP2C19PLA2G1B | |
| SCHEMBL3397984 | 0.84 | RAPGEF4 (0.50) | TSHRCYP3A4CYP2C9CYP2C19PLA2G1B | |
| SCHEMBL27511192 | 0.83 | ABL1 (0.55) | TSHRCYP3A4CYP2C9CYP2C19PLA2G1B | |
| Hydrochloric Acid SCHEMBL3395950 | 0.82 | RAPGEF4 (0.49) | TSHRCYP3A4CYP2C9CYP2C19PLA2G1B | |
| SCHEMBL29659123 | 0.81 | MAPT (0.46) | TSHRCYP3A4CYP2C9CYP2C19PLA2G1B | |
| SCHEMBL631579 | 0.81 | MAPT (0.46) | TSHRCYP3A4CYP2C9CYP2C19PLA2G1B | |
| SCHEMBL1799567 | 0.81 | CYP3A4 (0.53) | CYP3A4MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2528595-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES | INOXIA LIFESCIENCES GMBH (AT) | 2015-08-05 | — | — | EP | claimed |
| US-20110053985-A1 | NOVEL PIPERIDINE-4-CARBOXYLIC ACID PHENYL-ALKYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2011-03-03 | — | — | US | claimed |
| EP-2245011-A1 | NOVEL PIPERIDINE-4-CARBOXYLIC ACID PHENYL-ALKYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NeuroSearch A/S (DK) | 2010-11-03 | — | — | EP | claimed |
| WO-2009090173-A1 | NOVEL PIPERIDINE-4-CARBOXYLIC ACID PHENYL-ALKYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2009-07-23 | — | — | WO | claimed |
| US-20250325547-A1 | ANTI-SARS-COV-2 DRUG | KAGOSHIMA UNIVERSITY (JP) | 2025-10-23 | — | — | US | disclosed |
| US-12358886-B2 | Heterocyclic compounds for use in the treatment of cancer | ARTIOS PHARMA LIMITED (GB) | 2025-07-15 | — | — | US | disclosed |
| WO-2025016138-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | SUZHOU EOC MEDICAL RESEARCH CO., LTD. (CN) | 2025-01-23 | — | — | WO | disclosed |
| CN-114667167-B | Heterocyclic compounds for the treatment of cancer | 阿提奥斯医药有限公司 | 2024-12-20 | — | — | CN | disclosed |
| EP-4431151-A1 | ANTI-SARS-COV-2 DRUG | Kagoshima University (JP) | 2024-09-18 | — | — | EP | disclosed |
| CN-118302413-A | Anti-SARS-CoV-2 medicine | 国立大学法人鹿儿岛大学 | 2024-07-05 | — | — | CN | disclosed |
| US-20230322715-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-12 | — | — | US | disclosed |
| EP-4010080-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LTD (GB) | 2023-09-27 | — | — | EP | disclosed |
| EP-2245011-A1 | NOVEL PIPERIDINE-4-CARBOXYLIC ACID PHENYL-ALKYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NeuroSearch A/S (DK) | 2010-11-03 | — | — | EP | disclosed |
| US-20100113452-A1 | COMPOUNDS FOR TREATING PULMONARY HYPERTENSION | BAYER HEALTHCARE AG (DE) | 2010-05-06 | — | — | US | disclosed |
| WO-2009090173-A1 | NOVEL PIPERIDINE-4-CARBOXYLIC ACID PHENYL-ALKYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2009-07-23 | — | — | WO | disclosed |
| CN-1256328-C | Position seven substituted amine methyl fluoro quinolone derivative having antibacterial activity and its preparation method | SHANGHAI INST PHARM INDUSTRY (CN) | 2006-05-17 | — | — | CN | disclosed |
| CN-1493562-A | Position seven substituted amine methyl fluoro quinolone derivative having antibacterial activity and its preparation method | 上海医药工业研究院 | 2004-05-05 | — | — | CN | disclosed |
| CN-1303389-A | 3 ', 3' -N-disubstituted macrolide Luteinizing Hormone Releasing Hormone (LHRH) antagonists | ABBOTT LAB (US) | 2001-07-11 | — | — | CN | disclosed |
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |
| EP-0433648-A1 | Substituted pyrimidobenzimidazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053985-A1 | NOVEL PIPERIDINE-4-CARBOXYLIC ACID PHENYL-ALKYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | SLC18A2, SLC6A2, SLC18A3 | TSHR 1152/4885CYP3A4 510/4885CYP2C9 627/4885 |
| US-20100113452-A1 | COMPOUNDS FOR TREATING PULMONARY HYPERTENSION | PTGIR, PTGIS, EDNRB | TSHR 2041/4885CYP3A4 2340/4885CYP2C9 3227/4885 |
| US-20230322715-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | YTHDF1, YTHDF3, YTHDF2 | TSHR 2302/4885CYP3A4 4503/4885CYP2C9 4535/4885 |
| US-20250325547-A1 | ANTI-SARS-COV-2 DRUG | ACE2, ACE, AGTR2 | TSHR 27/4885CYP3A4 529/4885CYP2C9 823/4885 |
| US-12358886-B2 | Heterocyclic compounds for use in the treatment of cancer | SDHA, DPYD, TP53 | TSHR 3750/4885CYP3A4 70/4885CYP2C9 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.