Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938360 | 0.91 | POLB (0.36) | POLBEPHX2PTGESTAS2R14SLC2A1 | |
| SCHEMBL7945107 | 0.90 | POLB (0.36) | POLBEPHX2PTGESTAS2R14SLC2A1 | |
| SCHEMBL7947094 | 0.89 | POLB (0.37) | POLBEPHX2ALDH1A1MAPTMMP3 | |
| SCHEMBL7947164 | 0.88 | PLA2G2A (0.37) | POLBEPHX2PTGESTAS2R14SLC2A1 | |
| SCHEMBL7948016 | 0.86 | POLB (0.38) | POLBEPHX2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7986761 | 0.86 | HTT (0.36) | POLBALDH1A1MAPTL3MBTL1HTT | |
| SCHEMBL7946743 | 0.85 | MITF (0.45) | POLBEPHX2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7947285 | 0.85 | HPGD (0.36) | POLBALDH1A1L3MBTL1MMP3MMP1 | |
| SCHEMBL7969073 | 0.85 | MTNR1B (0.35) | POLBALDH1A1PTGDR2MEN1KMT2A | |
| SCHEMBL7951886 | 0.85 | MITF (0.45) | POLBEPHX2ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |