Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938360 | 0.90 | POLB (0.36) | POLBALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL7992668 | 0.89 | SIGMAR1 (0.45) | — | |
| SCHEMBL7945107 | 0.87 | POLB (0.36) | POLBALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7946077 | 0.86 | POLB (0.35) | HTTPOLBALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7947164 | 0.85 | PLA2G2A (0.37) | POLBALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL7951892 | 0.85 | POLB (0.39) | HTTMITFOPRK1PAX8POLB | |
| SCHEMBL7948614 | 0.84 | POLB (0.40) | POLBALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL7948016 | 0.84 | POLB (0.38) | HTTMITFOPRK1PAX8POLB | |
| SCHEMBL7946743 | 0.82 | MITF (0.45) | HTTMITFOPRK1PAX8POLB | |
| SCHEMBL7969073 | 0.82 | MTNR1B (0.35) | POLBALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |