Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947285 | 0.98 | HPGD (0.36) | MTNR1BPOLBHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7948263 | 0.98 | HPGD (0.36) | MTNR1BPOLBHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7938405 | 0.93 | FKBP1A (0.38) | POLBALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL7947164 | 0.87 | PLA2G2A (0.37) | POLBALDH1A1KMT2APTGDR2MEN1 | |
| SCHEMBL7938360 | 0.86 | POLB (0.36) | POLBALDH1A1KMT2APTGDR2MEN1 | |
| SCHEMBL7945107 | 0.86 | POLB (0.36) | POLBALDH1A1PTGDR2 | |
| SCHEMBL7948016 | 0.86 | POLB (0.38) | POLBSMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL7946077 | 0.85 | POLB (0.35) | POLBALDH1A1KMT2APTGDR2MEN1 | |
| SCHEMBL7982224 | 0.85 | RAB9A (0.34) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL7946743 | 0.84 | MITF (0.45) | POLBHPGDSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |