Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 5/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | BRAF | P15056 | 4/20 | 0.42 |
| ▸ | RAF1 | P04049 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945458 | 0.86 | MAPT (0.48) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL7939052 | 0.84 | ALDH1A1 (0.49) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL7938904 | 0.79 | SHMT2 (0.44) | MAPTMEN1KMT2AHTR2CNPC1 | |
| SCHEMBL6816067 | 0.79 | MAPT (0.61) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL7950802 | 0.78 | ALDH1A1 (0.54) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL6816114 | 0.78 | MAPT (0.59) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL7939128 | 0.76 | LMNA (0.52) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL7945542 | 0.74 | ALDH1A1 (0.67) | MAPTMEN1KMT2AGAANPC1 | |
| SCHEMBL7946627 | 0.73 | KMT2A (0.59) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL9807561 | 0.73 | MAP2K1 (0.54) | GAAKDRTRPV1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |