Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | STK4 | Q13043 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938939 | 0.85 | MAPT (0.56) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL7939052 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL7945458 | 0.82 | MAPT (0.48) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL6815313 | 0.80 | MAPT (0.59) | ALDH1A1MAPTMEN1KMT2APLA2G7 | |
| SCHEMBL7938904 | 0.79 | SHMT2 (0.44) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7946708 | 0.78 | MAPT (0.45) | MAPTMEN1KMT2AGAAPYGL | |
| SCHEMBL6815941 | 0.77 | MAPT (0.61) | ALDH1A1MAPTMEN1KMT2APLA2G7 | |
| SCHEMBL7939128 | 0.76 | LMNA (0.52) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL6815324 | 0.71 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2APLA2G7 | |
| SCHEMBL7945542 | 0.70 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |