Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | UBE2M | P61081 | 1/20 | 0.30 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947322 | 0.79 | ALDH1A1 (0.40) | SLC6A9ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL7979068 | 0.78 | PDE2A (0.40) | SLC6A9ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL7985982 | 0.77 | KMT2A (0.40) | SLC6A9ALDH1A1KDM4EHPGDUSP2 | |
| SCHEMBL7951889 | 0.72 | KMT2A (0.41) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL7947094 | 0.72 | POLB (0.37) | ALDH1A1KDM4ENPSR1MAPTPOLB | |
| SCHEMBL7945535 | 0.71 | KDM4E (0.41) | ALDH1A1KDM4ETSHRNPSR1MAPT | |
| SCHEMBL7948016 | 0.70 | POLB (0.38) | SLC6A9ALDH1A1KDM4ENPSR1MAPT | |
| SCHEMBL7948614 | 0.68 | POLB (0.40) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL7946743 | 0.68 | MITF (0.45) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL7951886 | 0.68 | MITF (0.45) | ALDH1A1KDM4EHPGDNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |