Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947322 | 0.89 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL7944575 | 0.85 | ALDH1A1 (0.40) | PDE2APDE3BPDE3AP2RY12PYGL | |
| SCHEMBL7951889 | 0.81 | KMT2A (0.41) | PDE3BPDE3AALDH1A1KDM4EHPGD | |
| SCHEMBL7985982 | 0.81 | KMT2A (0.40) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL7981921 | 0.80 | TSHR (0.40) | KDM4ETSHRMAPTUSP2SMN1; SMN2 | |
| SCHEMBL7945535 | 0.79 | KDM4E (0.41) | ALDH1A1KDM4ETSHRMAPTNPSR1 | |
| SCHEMBL7969242 | 0.79 | TP53 (0.41) | ALDH1A1KDM4ETSHRMAPTL3MBTL1 | |
| SCHEMBL7946774 | 0.78 | SLC6A9 (0.35) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL7945107 | 0.77 | POLB (0.36) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7948614 | 0.77 | POLB (0.40) | ALDH1A1KDM4EHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |