Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345646 | 0.78 | ADORA3 (0.48) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL794861 | 0.68 | ALDH1A1 (0.43) | ALDH1A1POLBNPC1RAB9AKMT2A | |
| SCHEMBL9018567 | 0.62 | ALDH1A1 (0.61) | PDPK1ALDH1A1POLBNPC1MAPK1 | |
| SCHEMBL2213286 | 0.60 | ALDH1A1 (0.59) | PDPK1ALDH1A1POLBNPC1MAPK1 | |
| SCHEMBL2909003 | 0.60 | MEN1 (0.52) | ADORA2AADORA1ALDH1A1POLBNPC1 | |
| Biphenyl SCHEMBL1358618 | 0.57 | ALDH1A1 (1.00) | ALDH1A1ALOX5NPC1MAPK1RAB9A | |
| Biphenyl SCHEMBL164 | 0.57 | ALDH1A1 (1.00) | ALDH1A1ALOX5NPC1MAPK1RAB9A | |
| SCHEMBL30108088 | 0.57 | ALDH1A1 (1.00) | ALDH1A1ALOX5NPC1MAPK1RAB9A | |
| Biphenyl SCHEMBL2548048 | 0.57 | ALDH1A1 (1.00) | ALDH1A1ALOX5NPC1MAPK1RAB9A | |
| Biphenyl SCHEMBL29008551 | 0.57 | ALDH1A1 (1.00) | ALDH1A1ALOX5NPC1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4284787-A | Process for the preparation of 1,2,3-triazoles substituted in the 2-position | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | claimed |
| CN-116406359-A | Bicyclo [1.1.1] pentanes for the treatment and prevention of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2023-07-07 | — | — | CN | disclosed |
| US-10206401-B2 | Pyridine compounds for controlling invertebrate pests II | BASF SE (DE) | 2019-02-19 | — | — | US | disclosed |
| US-20180116221-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | BASF SE (DE) | 2018-05-03 | — | — | US | disclosed |
| EP-2616458-B1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS II | BASF SE (DE) | 2016-07-20 | — | — | EP | disclosed |
| WO-2015124606-A1 | N-SUBSTITUTED IMINO HETEROCYCLIC COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2015-08-27 | — | — | WO | disclosed |
| US-8765791-B2 | Method of treating cancer using a neuropeptide Y 5R (NP Y5R) antagonist | UNIVERSITY HEALTH NETWORK (CA) | 2014-07-01 | — | — | US | disclosed |
| US-20130203821-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | BASF SE (DE) | 2013-08-08 | — | — | US | disclosed |
| EP-2616458-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS II | BASF SE (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034960-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS II | BASF SE (DE) | 2012-03-22 | — | — | WO | disclosed |
| US-20020052371-A1 | NOVEL SPIRO COMPOUNDS | MSD K.K. (JP) | 2002-05-02 | — | — | US | disclosed |
| EP-1165074-A2 | VIRAL TREATMENT | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6335345-B1 | NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; OBESITY AND BULIMIA TREATMENT; CENTRAL NERVOUS SYSTEM, PSYCHOLOGICAL, METABOLIC AND EATING DISORDERS; ANTIDIABETIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-01-01 | — | — | US | disclosed |
| US-6326375-B1 | CONTAINING AN UREA GROUP | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| WO-2000057869-A2 | VIRAL TREATMENT | THE PROCTER & GAMBLE COMPANY (US) | 2000-10-05 | — | — | WO | disclosed |
| US-4683227-A | CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| EP-0211526-A2 | Cephalosporins, their preparation and formulations | ELI LILLY AND COMPANY (US) | 1987-02-25 | — | — | EP | disclosed |
| US-4284787-A | Process for the preparation of 1,2,3-triazoles substituted in the 2-position | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |
| EP-0004897-B1 | PROCESS FOR THE PREPARATION OF 1,2,3 TRIAZOLES SUBSTITUTED IN THE 2-POSITION | BAYER AG (DE) | 1981-03-18 | — | — | EP | disclosed |
| EP-0004897-A2 | Process for the preparation of 1,2,3 triazoles substituted in the 2-position | BAYER AG (DE) | 1979-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052371-A1 | NOVEL SPIRO COMPOUNDS | GPR119, NPY1R, OPRK1 | ADORA3 2109/4885ADORA2A 2230/4885ADORA2B 2136/4885 |
| US-10206401-B2 | Pyridine compounds for controlling invertebrate pests II | PRXL2A, NR2C2, SHROOM3 | ADORA3 134/4885ADORA2A 126/4885ADORA2B 242/4885 |
| US-20180116221-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | PRXL2A, SHROOM3, NR2C2 | ADORA3 152/4885ADORA2A 133/4885ADORA2B 256/4885 |
| US-20130203821-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | GRIN2A, NR2C2, GRIA2 | ADORA3 142/4885ADORA2A 85/4885ADORA2B 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.