Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553224 | 0.68 | ATM (0.43) | TDP1ALDH1A1POLB | |
| SCHEMBL11815310 | 0.66 | ALDH1A1 (0.36) | TDP1ALDH1A1DDAH1ALOX5 | |
| SCHEMBL8683030 | 0.66 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL791983 | 0.65 | FFAR1 (0.49) | — | |
| SCHEMBL30097125 | 0.65 | FFAR1 (0.49) | — | |
| SCHEMBL27314236 | 0.64 | FFAR1 (0.45) | ALDH1A1 | |
| SCHEMBL29688708 | 0.64 | HSD11B1 (0.38) | ALDH1A1POLBALOX5 | |
| SCHEMBL8572575 | 0.63 | ALOX5 (0.34) | ALDH1A1ALOX5 | |
| SCHEMBL12701192 | 0.62 | MAPK1 (0.42) | ALDH1A1 | |
| SCHEMBL7081134 | 0.61 | ALDH1A1 (0.35) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262300-B1 | REACTING THE CORRESPONDING LACTONE WITH PHOSPGENE IN PRESENCE OF UREA | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-17 | — | — | US | disclosed |