Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.53 |
| ▸ | LIPE | Q05469 | 8/20 | 0.52 |
| ▸ | SCD | O00767 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956670 | 0.89 | LIPG (0.52) | LIPGLIPESCDMCHR1HCRTR1 | |
| SCHEMBL7961398 | 0.82 | LIPG (0.57) | LIPGLIPESCDMCHR1HCRTR1 | |
| SCHEMBL7961541 | 0.82 | LIPG (0.53) | LIPGLIPEHRH3 | |
| SCHEMBL13279901 | 0.81 | LIPG (0.55) | LIPGLIPEMCHR1HRH3 | |
| SCHEMBL7956574 | 0.78 | LIPG (0.57) | LIPGLIPESCDRETHRH3 | |
| SCHEMBL20147461 | 0.78 | LIPE (0.57) | LIPGLIPEHRH3 | |
| SCHEMBL20070180 | 0.77 | LIPE (0.57) | LIPGLIPE | |
| SCHEMBL20070188 | 0.77 | LIPE (0.56) | LIPGLIPEMCHR1HRH3ENPP2 | |
| SCHEMBL20145199 | 0.76 | LIPE (0.55) | LIPGLIPEHCRTR1 | |
| SCHEMBL7956524 | 0.75 | LIPG (0.60) | LIPGLIPESCDHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313127-B1 | FOR THERAPY OF HYPERCHOLESTEROLEMIA OR ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2001-11-06 | — | — | US | disclosed |