Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 6/20 | 0.35 |
| ▸ | CTSL | P07711 | 5/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836618 | 0.93 | MMP1 (0.36) | MEN1KMT2AMAPTPOLBMAPK1 | |
| SCHEMBL7849143 | 0.90 | HDAC1 (0.41) | SCN5ASCN9AHDAC3HDAC1HDAC2 | |
| SCHEMBL7838763 | 0.90 | MMP3 (0.36) | MEN1KMT2AMAPTPOLBNPSR1 | |
| SCHEMBL7838759 | 0.90 | MMP3 (0.36) | MEN1KMT2AMAPTPOLBNPSR1 | |
| SCHEMBL7850472 | 0.88 | MMP3 (0.37) | MEN1KMT2AMAPTPOLBNPSR1 | |
| SCHEMBL7838766 | 0.88 | MMP3 (0.37) | MEN1KMT2AMAPTPOLBNPSR1 | |
| SCHEMBL7955756 | 0.87 | ALDH1A1 (0.36) | MEN1KMT2AMAPTALDH1A1CTSK | |
| SCHEMBL7955753 | 0.87 | ALDH1A1 (0.36) | MEN1KMT2AMAPTALDH1A1CTSK | |
| SCHEMBL7848201 | 0.85 | L3MBTL1 (0.36) | MEN1KMT2AALDH1A1POLBSCN5A | |
| SCHEMBL7955667 | 0.85 | MMP1 (0.40) | MEN1KMT2AALDH1A1POLBMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281363-B1 | ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS; AUTOIMMUNE DISORDERS | HOFFMANN-LA ROCHE INC. | 2001-08-28 | — | — | US | disclosed |