Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100296 | 0.97 | CYP3A4 (0.38) | CYP3A4TSHRNFKB1NPSR1 | |
| SCHEMBL8674327 | 0.90 | CA2 (0.36) | CYP3A4TSHRNFKB1NPSR1 | |
| Potassium Ion SCHEMBL7100634 | 0.77 | CA2 (0.37) | NFKB1 | |
| Ammonia Solution, Strong SCHEMBL7101848 | 0.77 | CHRM1 (0.33) | — | |
| SCHEMBL7955205 | 0.77 | CHRM1 (0.33) | — | |
| SCHEMBL7100300 | 0.77 | CHRM1 (0.33) | — | |
| Potassium Ion SCHEMBL7095227 | 0.69 | CA1 (0.41) | NFKB1 | |
| Potassium Ion SCHEMBL11581382 | 0.68 | — | — | |
| Potassium Ion SCHEMBL7955201 | 0.67 | CYP3A4 (0.42) | CYP3A4TSHRNFKB1NPSR1 | |
| SCHEMBL7102090 | 0.66 | CA1 (0.44) | CYP3A4TSHRNFKB1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6261352-B1 | BETAINE, SULFO ESTER | THE PILOT INK CO., LTD. (JP) | 2001-07-17 | — | — | US | disclosed |
| EP-0964036-A2 | Water-based ball-point pen ink composition | THE PILOT INK CO., LTD. (JP) | 1999-12-15 | — | — | EP | disclosed |