Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954385 | 0.76 | RAB9A (0.62) | RAB9AGABRA1GABRG2GABRB3HTR3E | |
| SCHEMBL10898420 | 0.76 | ACHE (0.65) | BCHEACHERAB9AGABRA1GABRG2 | |
| SCHEMBL7954805 | 0.76 | ACHE (0.65) | BCHEACHEGABRA1GABRG2GABRB3 | |
| SCHEMBL10901959 | 0.76 | ACHE (0.65) | BCHEACHEGABRA1GABRG2GABRB3 | |
| SCHEMBL721717 | 0.73 | ACHE (1.00) | BCHEACHESLC6A4CHRM2CHRM4 | |
| SCHEMBL10902047 | 0.72 | ACHE (0.60) | BCHEACHERAB9AALDH1A1MEN1 | |
| SCHEMBL2874836 | 0.72 | BCHE (0.59) | BCHEACHEGABRA1GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL9937223 | 0.72 | ACHE (0.97) | BCHEACHESLC6A4CHRM2CHRM4 | |
| SCHEMBL7965539 | 0.71 | ALDH1A1 (0.46) | RAB9AGABRA1GABRG2GABRB3CHRNB4 | |
| SCHEMBL7967192 | 0.71 | KCNH2 (0.48) | ACHERAB9AGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303627-B1 | FOR THERAPY OF PHYSIOLOGICAL AND PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY | 2001-10-16 | — | — | US | disclosed |
| WO-1999065487-A1 | INHIBITORS OF SEROTONIN REUPTAKE | ELI LILLY AND COMPANY (US) | 1999-12-23 | — | — | WO | disclosed |
| EP-0965587-A1 | Tetrahydropyridinyl- and piperidinyl Inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1999-12-22 | — | — | EP | disclosed |