Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 5/20 | 0.44 |
| ▸ | TYMS | P04818 | 2/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955950 | 0.83 | DHFR (0.49) | DHFRTYMSUTS2RKDM4EALDH1A1 | |
| SCHEMBL7965270 | 0.83 | DHFR (0.47) | DHFRTYMSUTS2RTSHRHTT | |
| SCHEMBL7956082 | 0.80 | DHFR (0.37) | DHFRTYMSKDM4EALDH1A1HPGD | |
| SCHEMBL7968559 | 0.77 | DHFR (0.39) | DHFRTYMSUTS2RKDM4EALDH1A1 | |
| SCHEMBL7969034 | 0.76 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL7983353 | 0.76 | CHRNA1 (0.42) | DHFRKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL7984718 | 0.76 | CHRNA1 (0.42) | DHFRKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL6026477 | 0.74 | CHRNA1 (0.39) | KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL7984729 | 0.74 | CHRNA1 (0.39) | KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL7968952 | 0.74 | KDM4E (0.38) | DHFRKDM4EALDH1A1HPGDPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |