Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313109 | 0.82 | TSHR (0.46) | TSHRALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL2476137 | 0.76 | L3MBTL1 (0.46) | MEN1LMNAKMT2AESR1NPSR1 | |
| SCHEMBL8754731 | 0.70 | LMNA (0.48) | ALDH1A1HSD17B10TDP1MEN1LMNA | |
| SCHEMBL11477000 | 0.70 | CA2 (0.41) | TSHRALDH1A1TDP1SMN1; SMN2HSP90AA1 | |
| SCHEMBL27576782 | 0.69 | ESR1 (0.48) | TSHRALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL11598690 | 0.68 | MAPT (0.47) | TSHRALDH1A1TDP1MEN1LMNA | |
| SCHEMBL3045678 | 0.67 | KMT2A (0.46) | TSHRALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL450584 | 0.67 | ESR1 (0.52) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9827589 | 0.66 | HSD17B1 (0.61) | TSHRALDH1A1HSD17B10HSD17B1HSD17B2 | |
| SCHEMBL8924255 | 0.65 | PKM (0.50) | TSHRALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271355-B1 | USEFUL FOR THE COLORATION OF E.G. CELLULOSIC MATERIALS AND LEATHERS. | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2001-08-07 | — | — | US | disclosed |
| EP-0471456-B1 | Dyes | ZENECA LTD (GB) | 1995-09-20 | — | — | EP | disclosed |
| EP-0471456-A1 | Dyes | ZENECA LIMITED (GB) | 1992-02-19 | — | — | EP | disclosed |