Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.39 |
| ▸ | PTGIR | P43119 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956033 | 0.89 | F2RL3 (0.43) | ADORA3ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL7958971 | 0.78 | ALDH1A1 (0.49) | ADORA3ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL7948818 | 0.78 | KDM4E (0.45) | ADORA3ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL7956256 | 0.76 | PTGIR (0.45) | ADORA3ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL7958318 | 0.74 | PTGIR (0.43) | ADORA3ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL7958975 | 0.74 | KDM4E (0.46) | ADORA3ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL7956745 | 0.73 | PTGIR (0.47) | ADORA3ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL7956747 | 0.68 | PTGIR (0.58) | KDM4EALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL7967332 | 0.68 | MAPT (0.48) | ADORA3ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL10669176 | 0.66 | LMNA (0.58) | ADORA2AADORA1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |