Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 3/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7958543 | 0.75 | MCHR1 (0.46) | METAP1MCHR1CA1CA2ACHE | |
| Hydrochloric Acid SCHEMBL4623245 | 0.74 | METAP1 (0.49) | METAP1MCHR1CYP19A1CYP26A1SLC6A2 | |
| SCHEMBL3247442 | 0.70 | ALOX15 (0.40) | MTNR1A | |
| SCHEMBL13937919 | 0.68 | HTR5A (0.44) | ACHECYP19A1HTR5AHTR2AHTR2C | |
| SCHEMBL3241271 | 0.67 | GAA (0.57) | CA1CA2ACHEMTNR1AHTR5A | |
| Hydrochloric Acid SCHEMBL4623292 | 0.66 | CYP19A1 (0.59) | METAP1MCHR1CA1CA2ACHE | |
| Hydrochloric Acid SCHEMBL4622581 | 0.66 | MCHR1 (0.59) | METAP1MCHR1CA1CA2ACHE | |
| SCHEMBL28634734 | 0.66 | MTNR1A (0.44) | CA1CA2ACHEMTNR1AHTR5A | |
| SCHEMBL4999513 | 0.66 | MTNR1A (0.44) | CA1CA2ACHEMTNR1AHTR5A | |
| SCHEMBL1321069 | 0.64 | ALOX15 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329389-B1 | HETEROCYCLIC AMINES AND DERIVATIVES, SOMATOSTATIN AND ANTIDIABETIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-11 | — | — | US | disclosed |