Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3043496 | 0.81 | MAPT (0.45) | ALDH1A1KDM4EL3MBTL1MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL3052246 | 0.80 | MAPT (0.44) | ALDH1A1KDM4EL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL1321069 | 0.79 | ALOX15 (0.44) | ALOX15ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL13937919 | 0.76 | HTR5A (0.44) | — | |
| SCHEMBL7309997 | 0.73 | PDE3B (0.41) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL17049209 | 0.72 | ALDH1A1 (0.48) | ALOX15ALDH1A1KDM4EHPGDNPC1 | |
| Hydrochloric Acid SCHEMBL7313862 | 0.72 | PDE3B (0.40) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL3241271 | 0.71 | GAA (0.57) | ALDH1A1HPGDMTNR1AMTNR1BMAPT | |
| SCHEMBL3250596 | 0.70 | ALOX15 (0.43) | ALOX15ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL7958545 | 0.70 | METAP1 (0.43) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066318-B1 | OXINDOLE DERIVATIVES AS ANTICANCER AGENTS | HOFFMANN LA ROCHE (CH) | 2010-05-12 | — | — | EP | claimed |