Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPY1R | P25929 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959187 | 0.85 | NPY1R (0.56) | ALDH1A1NPY1RMAPTHPGDSMN1; SMN2 | |
| SCHEMBL7959114 | 0.84 | SMN1; SMN2 (0.50) | ALDH1A1RAB9ANPY1RMAPTSMN1; SMN2 | |
| SCHEMBL7965110 | 0.75 | RAB9A (0.55) | ALDH1A1RXFP1RAB9AMAPTHPGD | |
| SCHEMBL7959599 | 0.74 | P2RX7 (0.51) | ALDH1A1NPY1RMAPTHPGDKDM4E | |
| SCHEMBL15444518 | 0.73 | ALDH1A1 (0.97) | ALDH1A1MAPTSMN1; SMN2POLBKMT2A | |
| Hydrochloric Acid SCHEMBL7960992 | 0.70 | NPY1R (0.60) | ALDH1A1RAB9ANPY1RMAOBMAPT | |
| Hydrochloric Acid SCHEMBL7956693 | 0.70 | NPY1R (0.77) | ALDH1A1NPY1RSMN1; SMN2TSHRMEN1 | |
| SCHEMBL15154582 | 0.70 | MEN1 (0.77) | ALDH1A1RXFP1RAB9AMAOBMAPT | |
| Hydrochloric Acid SCHEMBL7959270 | 0.69 | NPY1R (0.64) | ALDH1A1NPY1RSMN1; SMN2TSHRMEN1 | |
| SCHEMBL7957280 | 0.69 | NPY1R (0.66) | ALDH1A1RAB9ANPY1RMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| CN-1173867-A | Indolyl neuropeptide Y receptor antagonists | LILLY CO ELI (US) | 1998-02-18 | — | — | CN | disclosed |