Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | DVL1 | O14640 | 1/20 | 0.52 |
| ▸ | DVL3 | Q92997 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959599 | 0.84 | P2RX7 (0.51) | NPC1ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL7960784 | 0.77 | NPY1R (0.54) | ALDH1A1KDM4EHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL7959114 | 0.76 | SMN1; SMN2 (0.50) | RAB9ANPC1GAAALDH1A1KDM4E | |
| SCHEMBL7958725 | 0.75 | ALDH1A1 (0.55) | RAB9ANPC1GAAALDH1A1KDM4E | |
| SCHEMBL7959187 | 0.75 | NPY1R (0.56) | ALDH1A1KDM4EPOLBMAPTSMN1; SMN2 | |
| SCHEMBL19691170 | 0.73 | RAB9A (0.52) | RAB9ANPC1GAAPPARGNCOA2 | |
| Hydrochloric Acid SCHEMBL7958855 | 0.72 | NPY1R (0.51) | ALDH1A1KDM4EHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL1787246 | 0.72 | MCHR1 (0.54) | ALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL23421824 | 0.71 | TP53 (0.54) | ALDH1A1KDM4EPOLBTSHRTP53 | |
| SCHEMBL22449380 | 0.71 | ALDH1A1 (0.75) | RAB9ANPC1GAAPPARGNCOA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| CN-1173867-A | Indolyl neuropeptide Y receptor antagonists | LILLY CO ELI (US) | 1998-02-18 | — | — | CN | disclosed |