SCHEMBL7959878

SCHEMBL7959878

O=C(O)NS(=O)(=O)c1ccccn1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.51
NLRP3 Q96P20 1/20 0.51
PTGS2 P35354 4/20 0.50
METAP2 P50579 1/20 0.50
KAT6A Q92794 1/20 0.49
MMP2 P08253 3/20 0.48
GLO1 Q04760 2/20 0.46
SLC40A1 Q9NP59 2/20 0.46
PTGS1 P23219 1/20 0.43
P4HTM Q9NXG6 2/20 0.42
LMNA P02545 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
KDM4E B2RXH2 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25294544 0.84 P4HTM (0.56) L3MBTL1NLRP3PTGS2KAT6APTGS1
SCHEMBL16549739 0.84 PKM (0.55) L3MBTL1NLRP3PTGS2METAP2KAT6A
SCHEMBL729640 0.84 L3MBTL1 (0.50) L3MBTL1NLRP3PTGS2METAP2KAT6A
SCHEMBL18157894 0.81 PTGS2 (0.71) L3MBTL1NLRP3PTGS2METAP2PTGS1
SCHEMBL20000432 0.80 ALDH1A1 (0.49) L3MBTL1NLRP3PTGS2METAP2KAT6A
SCHEMBL10430944 0.80 NLRP3 (0.47) L3MBTL1NLRP3PTGS2METAP2KAT6A
SCHEMBL17943674 0.80 KDM4E (0.49) L3MBTL1NLRP3PTGS2METAP2KAT6A
SCHEMBL7669511 0.80 NLRP3 (0.60) L3MBTL1NLRP3PTGS2METAP2KAT6A
SCHEMBL7020551 0.79 METAP2 (0.49) L3MBTL1NLRP3PTGS2METAP2KAT6A
SCHEMBL9370312 0.79 L3MBTL1 (0.49) L3MBTL1NLRP3PTGS2METAP2KAT6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316388-B1 ANTIGROWTH AGENTS FOR PLANTS HOECHST SCHERING AGREVO GMBH (DE) 2001-11-13 US claimed
US-5714436-A PRE- AND POSTEMERGENCE HERBICIDES; RICE; CROPS; MONO- AND DICOTYLEDONS HOECHST SCHERING AGREVO GMBH (DE) 1998-02-03 US claimed
EP-0715629-B1 N-HETEROARYL-N'(PYRID-2-YL-SULPHONYL) UREAS, PROCESSES FOR THE MANUFACTURE THEREOF, USES THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1997-01-29 EP claimed
EP-0510032-B1 USE OF PYRIDYL SULPHONYL UREAS AS HERBICIDES AND PLANT GROWTH REGULATORS, PROCESS FOR PRODUCING THEM AND THEIR USE HOECHST SCHERING AGREVO GMBH (DE) 1996-11-13 EP claimed
EP-0715629-A1 N-HETEROARYL-N'(PYRID-2-YL-SULPHONYL) UREAS, PROCESSES FOR THE MANUFACTURE THEREOF, USES THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1996-06-12 EP claimed
WO-1995006049-A1 N-HETEROARYL-N'(PYRID-2-YL-SULPHONYL) UREAS, PROCESSES FOR THE MANUFACTURE THEREOF, USES THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1995-03-02 WO claimed
EP-0555770-A1 N-Heteroaryl-N'-(pyrid-2-yl-sulfonyl)-ureas, process for their preparation, and their use as herbicides and plant growth regulators Hoechst Schering AgrEvo GmbH (DE) 1993-08-18 EP claimed
EP-0510032-A1 USE OF PYRIDYL SULPHONYL UREAS AS HERBICIDES AND PLANT GROWTH REGULATORS, PROCESS FOR PRODUCING THEM AND THEIR USE. HOECHST AG (DE) 1992-10-28 EP claimed
WO-1991010660-A1 USE OF PYRIDYL SULPHONYL UREAS AS HERBICIDES AND PLANT GROWTH REGULATORS, PROCESS FOR PRODUCING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-25 WO claimed
EP-0145664-B1 HERBICIDAL SULFONYL UREAS CIBA-GEIGY AG (CH) 1988-04-27 EP claimed
EP-0103543-B1 SULFONYL UREAS CIBA-GEIGY AG (CH) 1987-09-30 EP claimed
EP-0103543-A2 Sulfonyl ureas CIBA-GEIGY AG (CH) 1984-03-21 EP claimed
US-6316388-B1 ANTIGROWTH AGENTS FOR PLANTS HOECHST SCHERING AGREVO GMBH (DE) 2001-11-13 US disclosed
US-5847146-A N-heteroartyl-n'-(pyrid-2yl-sulfonyl) ureas, processes for their preparation, and their use as herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 1998-12-08 US disclosed
US-5714436-A PRE- AND POSTEMERGENCE HERBICIDES; RICE; CROPS; MONO- AND DICOTYLEDONS HOECHST SCHERING AGREVO GMBH (DE) 1998-02-03 US disclosed
US-5663118-A Fluoromethylsulfonyl-substituted pyridylsulfonylureas as herbicides, process for their preparation, and their use HOECHST SCHERING AGREVO GMBH (DE) 1997-09-02 US disclosed
EP-0103543-A2 Sulfonyl ureas CIBA-GEIGY AG (CH) 1984-03-21 EP disclosed
EP-0003383-B1 4-AMINO-3-SULFONAMIDO PYRIDINE DERIVATIVES A. CHRISTIAENS SOCIETE ANONYME (BE) 1983-02-09 EP disclosed
US-4244950-A DIURETICS A. CHRISTIAENS SOCIETE ANONYME (BE) 1981-01-13 US disclosed
EP-0003383-A2 4-Amino-3-sulfonamido pyridine derivatives A. CHRISTIAENS SOCIETE ANONYME (BE) 1979-08-08 EP disclosed