Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 5/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | PARL | Q9H300 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12748792 | 0.73 | AKR1C3 (0.55) | KMT2AMEN1AKR1C3AKR1C1ALDH1A1 | |
| SCHEMBL5790264 | 0.70 | HTR6 (0.49) | KMT2AMEN1PLK1LMNASMN1; SMN2 | |
| SCHEMBL8568212 | 0.69 | CTDSP1 (0.40) | LMNAALDH1A1HTR6MAPT | |
| SCHEMBL22289952 | 0.64 | FABP4 (0.37) | KMT2AFABP4FABP3KDM4EALDH1A1 | |
| SCHEMBL7961094 | 0.62 | HTR6 (0.47) | KMT2AMEN1LMNAPARLALDH1A1 | |
| SCHEMBL19725538 | 0.61 | MAPT (0.59) | KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL22289935 | 0.61 | FABP4 (0.35) | KMT2APTGDR2FABP4FABP3KDM4E | |
| SCHEMBL7799771 | 0.59 | LMNA (0.68) | KMT2AMEN1PLK1LMNASMN1; SMN2 | |
| SCHEMBL9788974 | 0.59 | KLKB1 (0.47) | KMT2AMEN1PLK1LMNASMN1; SMN2 | |
| SCHEMBL27622290 | 0.59 | LMNA (0.72) | KMT2AMEN1PLK1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |