Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961210 | 0.83 | L3MBTL1 (0.32) | L3MBTL1MEN1KMT2AICMTDPP4 | |
| SCHEMBL7961222 | 0.83 | OPRM1 (0.36) | L3MBTL1MEN1KMT2AICMTDPP4 | |
| SCHEMBL2437957 | 0.73 | DPP4 (0.44) | L3MBTL1MEN1KMT2ADPP4SLC6A4 | |
| SCHEMBL27851037 | 0.71 | MAOA (0.47) | L3MBTL1MEN1KMT2AICMTDPP4 | |
| SCHEMBL7971401 | 0.65 | LMNA (0.40) | MEN1KMT2AMMP2MMP3MMP9 | |
| SCHEMBL7974408 | 0.63 | EPHX2 (0.39) | L3MBTL1MEN1KMT2AMMP2MMP3 | |
| SCHEMBL7972666 | 0.58 | CYP4F2 (0.45) | — | |
| SCHEMBL5264224 | 0.58 | TACR1 (0.49) | SLC6A4 | |
| SCHEMBL5593684 | 0.58 | KCNA3 (0.64) | ALDH1A1 | |
| SCHEMBL7500091 | 0.58 | KCNA3 (0.64) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |