Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ICMT | O60725 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961210 | 0.86 | L3MBTL1 (0.32) | L3MBTL1MEN1KMT2ADPP4SLC6A4 | |
| SCHEMBL7961297 | 0.83 | L3MBTL1 (0.33) | L3MBTL1MEN1KMT2ADPP4SLC6A4 | |
| SCHEMBL7971401 | 0.78 | LMNA (0.40) | OPRM1OPRL1MEN1KMT2AEPHX2 | |
| SCHEMBL7973063 | 0.76 | MMP2 (0.32) | OPRM1OPRL1TSHR | |
| SCHEMBL7972666 | 0.72 | CYP4F2 (0.45) | CYP4F2CYP4A11 | |
| SCHEMBL15795307 | 0.69 | SLC6A4 (0.54) | OPRM1OPRL1L3MBTL1MEN1KMT2A | |
| SCHEMBL7974393 | 0.67 | CYP4F2 (0.46) | CYP4F2CYP4A11 | |
| SCHEMBL7974408 | 0.66 | EPHX2 (0.39) | L3MBTL1MEN1KMT2AEPHX2ALDH1A1 | |
| SCHEMBL7974599 | 0.66 | CYP4F2 (0.44) | L3MBTL1MEN1KMT2AALDH1A1CYP4F2 | |
| SCHEMBL27377646 | 0.65 | HTR2A (0.46) | OPRM1OPRL1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| EP-0968164-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998033758-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-06 | — | — | WO | disclosed |