Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961505 | 0.96 | L3MBTL1 (0.43) | POLBMAPTPKMCA2CA1 | |
| SCHEMBL27660967 | 0.78 | NPC1 (0.48) | MAPTTLR8UTS2RTLR7NPC1 | |
| SCHEMBL7961503 | 0.77 | L3MBTL1 (0.42) | POLBMAPTPKMTLR8UTS2R | |
| SCHEMBL19897481 | 0.76 | BACE1 (0.54) | TLR8UTS2RTLR7NPC1KDM6B | |
| SCHEMBL8120618 | 0.76 | LMNA (0.40) | POLBCA2CA1CA9KDM4E | |
| SCHEMBL9020830 | 0.76 | CA1 (0.55) | MAPTCA2CA1CA9KDM4E | |
| SCHEMBL7991708 | 0.75 | CA2 (0.56) | POLBMAPTPKMCA2CA1 | |
| SCHEMBL28202900 | 0.74 | CA2 (0.44) | CA2CA1CA9TLR8TSHR | |
| SCHEMBL1974279 | 0.73 | KDM4E (0.47) | POLBTLR8UTS2RTLR7NPC1 | |
| SCHEMBL30692781 | 0.73 | NPC1 (0.47) | TLR8UTS2RTLR7NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336773-A | Herbicides; plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1994-08-09 | — | — | US | claimed |
| EP-0459949-B1 | Sulfonyl ureas with herbicidal activity and useful as plant growth regulators | CIBA GEIGY AG (CH) | 1996-01-03 | — | — | EP | disclosed |
| US-5336773-A | Herbicides; plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1994-08-09 | — | — | US | disclosed |
| US-5221315-A | Herbicides and plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1993-06-22 | — | — | US | disclosed |
| EP-0459949-A1 | Sulfonyl ureas with herbicidal activity and useful as plant growth regulators | CIBA-GEIGY AG (CH) | 1991-12-04 | — | — | EP | disclosed |