Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 7/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 11/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5996608 | 0.87 | PARP1 (0.39) | KMT2AMEN1MAPK1RAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7723748 | 0.86 | PARP1 (0.38) | KMT2AMEN1MAPK1RAB9AL3MBTL1 | |
| SCHEMBL7722975 | 0.77 | HTR1A (0.43) | — | |
| Hydrochloric Acid SCHEMBL7882760 | 0.76 | HTR1A (0.42) | MAPTLMNA | |
| SCHEMBL7961285 | 0.74 | ALDH1A1 (0.37) | KMT2AMEN1MAPK1RAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7727011 | 0.74 | KDM4E (0.43) | KMT2AMEN1MAPK1RAB9AL3MBTL1 | |
| SCHEMBL7722008 | 0.69 | CDK4 (0.35) | KMT2AMEN1MAPK1RAB9AL3MBTL1 | |
| SCHEMBL7723028 | 0.69 | CDK4 (0.35) | KMT2AMEN1MAPK1RAB9AL3MBTL1 | |
| SCHEMBL29614674 | 0.69 | PARP1 (0.43) | KMT2AMEN1MAPK1RAB9AL3MBTL1 | |
| SCHEMBL7718684 | 0.68 | GSK3B (0.41) | KMT2AMEN1MAPTALDH1A1ALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207680-B1 | FOR THERAPY OF PSYCHOLOGICAL DISORDERS AND PAIN | AVENTIS PHARMACEUTICALS INC. | 2001-03-27 | — | — | US | disclosed |