Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | F8 | P00451 | 1/20 | 0.45 |
| ▸ | F5 | P12259 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964392 | 0.87 | CYP1A2 (0.58) | CYP1A2CYP2D6MEN1KMT2AUSP2 | |
| SCHEMBL7965119 | 0.83 | OPRM1 (0.39) | CYP1A2CYP2D6MEN1KMT2ANPSR1 | |
| SCHEMBL7965112 | 0.81 | LMNA (0.39) | CYP1A2CYP2D6KMT2AUSP2NPSR1 | |
| SCHEMBL7963395 | 0.80 | LMNA (0.44) | CYP1A2CYP2D6MEN1KMT2ANPSR1 | |
| SCHEMBL7962698 | 0.79 | L3MBTL1 (0.46) | CYP2D6MEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL7962210 | 0.79 | TP53 (0.56) | MEN1KMT2AMAPTSMN1; SMN2TP53 | |
| SCHEMBL7964941 | 0.78 | CCR1 (0.45) | CYP1A2MEN1KMT2ANPSR1MAPT | |
| SCHEMBL7962746 | 0.77 | SMN1; SMN2 (0.47) | USP2HTTNPSR1MAPTSMN1; SMN2 | |
| Fumaric Acid SCHEMBL7966212 | 0.75 | ABCB1 (0.51) | MEN1KMT2AHTTMAPTSMN1; SMN2 | |
| SCHEMBL7965174 | 0.74 | KMT2A (0.52) | KMT2AMAPTSMN1; SMN2ABCB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |