Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 2/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6196008 | 0.80 | ADRA1D (0.62) | KCNA3ADRA1DADRA1AADRA1BOPRM1 | |
| SCHEMBL11567071 | 0.78 | CA12 (0.48) | ADRA1DADRA1AADRA1BOPRM1OPRD1 | |
| SCHEMBL6961790 | 0.78 | KCNA3 (0.63) | KCNA3ADRA1DADRA1AADRA1BOPRM1 | |
| SCHEMBL7965695 | 0.77 | ADRA1D (0.61) | KCNA3ADRA1DADRA1AADRA1BOPRM1 | |
| SCHEMBL8416982 | 0.75 | KCNA3 (0.51) | KCNA3ADRA1AOPRM1OPRD1OPRK1 | |
| SCHEMBL14534189 | 0.74 | OPRM1 (0.71) | KCNA3ADRA1DADRA1AADRA1BOPRM1 | |
| SCHEMBL7083719 | 0.74 | POLB (0.56) | — | |
| SCHEMBL6746046 | 0.74 | KDM4E (0.60) | KCNA3ADRA1DADRA1AADRA1BOPRM1 | |
| Hydrochloric Acid SCHEMBL8419906 | 0.73 | SIGMAR1 (0.41) | ADRA1DADRA1AADRA1BOPRM1GAA | |
| SCHEMBL7313939 | 0.73 | KCNA3 (1.00) | KCNA3ADRA1AOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268369-B1 | ALPHA SUB 1 INHIBITORS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2001-07-31 | — | — | US | disclosed |