Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965276 | 0.90 | HSPB1 (0.40) | POLBMAPK1KMT2AMEN1MAPT | |
| SCHEMBL7539856 | 0.86 | ABCG2 (0.37) | POLBMAPK1MAPTRAB9A | |
| SCHEMBL6932601 | 0.85 | CFTR (0.43) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7971836 | 0.81 | APP (0.49) | POLBKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL6026158 | 0.81 | CFTR (0.50) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7956413 | 0.80 | CFTR (0.39) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL7966642 | 0.80 | CYP1A2 (0.41) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL6026268 | 0.80 | CFTR (0.39) | POLBKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL7966269 | 0.79 | LMNA (0.40) | POLBMAPTALDH1A1LMNAMMP2 | |
| SCHEMBL6932670 | 0.79 | MDM2 (0.38) | POLBKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |