Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027688 | 0.87 | CYP3A4 (0.40) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL6028062 | 0.79 | CYP3A4 (0.41) | MAPTRAB9ALMNASMN1; SMN2MEN1 | |
| SCHEMBL7968407 | 0.79 | POLB (0.46) | MAPTNPC1RAB9AMMP2MMP9 | |
| SCHEMBL7971836 | 0.78 | APP (0.49) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7965276 | 0.77 | HSPB1 (0.40) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL7968549 | 0.77 | MAPT (0.41) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL7966269 | 0.77 | LMNA (0.40) | MAPTNPC1RAB9AMMP2MMP9 | |
| SCHEMBL7968467 | 0.77 | MAPT (0.39) | MAPTNPC1RAB9ALMNAMEN1 | |
| SCHEMBL6932932 | 0.75 | MDM2 (0.38) | MAPTNPC1RAB9AMMP2MMP9 | |
| SCHEMBL7539856 | 0.74 | ABCG2 (0.37) | MAPTRAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |