Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptanoate SCHEMBL7966354 | 0.71 | LTA4H (0.38) | L3MBTL1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL7962698 | 0.70 | L3MBTL1 (0.46) | L3MBTL1KDM4EMAPK1CYP2D6TSHR | |
| SCHEMBL7969310 | 0.69 | L3MBTL1 (0.51) | L3MBTL1KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL7966053 | 0.68 | MAPT (0.36) | KDM4ELMNAHTR7POLBALDH1A1 | |
| SCHEMBL7962210 | 0.68 | TP53 (0.56) | L3MBTL1KDM4EMAPK1TSHRMEN1 | |
| SCHEMBL13898527 | 0.66 | L3MBTL1 (0.63) | L3MBTL1KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL19017558 | 0.65 | KDM4E (0.58) | KDM4EMEN1LMNAKMT2AMAPT | |
| SCHEMBL17991054 | 0.65 | KDM4E (0.58) | KDM4EMEN1LMNAKMT2AMAPT | |
| SCHEMBL7962746 | 0.65 | SMN1; SMN2 (0.47) | L3MBTL1KDM4EMAPK1NPSR1POLB | |
| SCHEMBL7969553 | 0.65 | L3MBTL1 (0.55) | L3MBTL1KDM4ECYP2D6TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |