Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RRM1 | P23921 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953454 | 0.85 | PRMT5 (0.47) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL7962746 | 0.84 | SMN1; SMN2 (0.47) | L3MBTL1KDM4EUSP2HSD17B10MAPK1 | |
| SCHEMBL7962210 | 0.83 | TP53 (0.56) | L3MBTL1KDM4ETSHRMAPK1KMT2A | |
| SCHEMBL7962701 | 0.81 | LTA4H (0.36) | KMT2AMEN1 | |
| SCHEMBL7962696 | 0.80 | LTA4H (0.35) | L3MBTL1KDM4ERAB9AKMT2AMEN1 | |
| SCHEMBL7965117 | 0.79 | CYP1A2 (0.58) | CYP2D6ATMUSP2KMT2AMEN1 | |
| Sulfuric Acid SCHEMBL7968960 | 0.78 | ADORA2A (0.39) | KDM4EPKMPRMT5WDR77SMN1; SMN2 | |
| SCHEMBL7963395 | 0.78 | LMNA (0.44) | KDM4ETSHRCYP2D6HIF1AKMT2A | |
| SCHEMBL7969553 | 0.76 | L3MBTL1 (0.55) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL7969310 | 0.75 | L3MBTL1 (0.51) | L3MBTL1KDM4ETSHRCYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |