Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966055 | 0.86 | LMNA (0.32) | TP53LMNA | |
| SCHEMBL7966355 | 0.68 | L3MBTL1 (0.40) | MAPTHTR7POLBKDM4EALDH1A1 | |
| SCHEMBL8133874 | 0.66 | ABCB1 (0.42) | ALDH1A1 | |
| SCHEMBL7962210 | 0.66 | TP53 (0.56) | MAPTTP53POLBKDM4EALDH1A1 | |
| SCHEMBL7965117 | 0.65 | CYP1A2 (0.58) | MAPTTP53LMNAGAAHTT | |
| SCHEMBL7962698 | 0.64 | L3MBTL1 (0.46) | KDM4ECYP2C19GAA | |
| Sulfuric Acid SCHEMBL7968960 | 0.63 | ADORA2A (0.39) | POLBKCNH2KDM4ELMNAGAA | |
| SCHEMBL7962746 | 0.63 | SMN1; SMN2 (0.47) | MAPTPOLBKDM4EHTT | |
| Fumaric Acid SCHEMBL7966212 | 0.63 | ABCB1 (0.51) | MAPTALDH1A1LMNAHTT | |
| SCHEMBL7953572 | 0.61 | KMT2A (0.54) | MAPTKDM4EALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |