Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971836 | 0.86 | APP (0.49) | MEN1KMT2AMAPTSMN1; SMN2TDP1 | |
| SCHEMBL7965678 | 0.82 | HSD17B1 (0.37) | PGRHSD17B1HSD17B2LMNAMAPT | |
| SCHEMBL7971994 | 0.82 | PGR (0.37) | PGRHSD17B1HSD17B2NQO2ESR1 | |
| SCHEMBL6026268 | 0.81 | CFTR (0.39) | MEN1KMT2AESR1ESR2LMNA | |
| SCHEMBL6932601 | 0.80 | CFTR (0.43) | MEN1KMT2AESR1ESR2LMNA | |
| SCHEMBL6026158 | 0.78 | CFTR (0.50) | MEN1KMT2AESR1ESR2LMNA | |
| SCHEMBL6026391 | 0.76 | MCL1 (0.42) | MEN1KMT2AESR1ESR2LMNA | |
| SCHEMBL6027636 | 0.75 | ALDH1A1 (0.36) | NQO2MEN1KMT2AESR1ESR2 | |
| SCHEMBL7956413 | 0.75 | CFTR (0.39) | MEN1KMT2AESR1ESR2LMNA | |
| SCHEMBL7966642 | 0.75 | CYP1A2 (0.41) | MEN1KMT2AESR1ESR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |