Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 4/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | WRN | Q14191 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972438 | 0.82 | ESR2 (0.42) | ESR1ESR2HCAR3HCAR2QPCT | |
| SCHEMBL7967042 | 0.82 | PGR (0.36) | PGRAPPESR1ESR2SLC6A7 | |
| SCHEMBL6026628 | 0.80 | MEN1 (0.37) | HCAR3HCAR2 | |
| SCHEMBL7971836 | 0.78 | APP (0.49) | APP | |
| SCHEMBL7984718 | 0.78 | CHRNA1 (0.42) | HCAR3HCAR2HDAC1 | |
| SCHEMBL6932927 | 0.78 | CHRNA1 (0.42) | HCAR3HCAR2HDAC1 | |
| SCHEMBL7966664 | 0.76 | HCAR2 (0.46) | PGRCYP3A4CYP2C19HCAR3HCAR2 | |
| SCHEMBL6934036 | 0.76 | PTGS2 (0.37) | HCAR3HCAR2 | |
| SCHEMBL7030070 | 0.76 | HCAR2 (0.46) | PGRCYP3A4CYP2C19HCAR3HCAR2 | |
| SCHEMBL7593441 | 0.76 | ALDH1A1 (0.38) | PGRHCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |