Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29169997 | 0.88 | HCRTR2 (0.34) | TDP1HCRTR2GAAMEN1KMT2A | |
| SCHEMBL24071385 | 0.85 | P2RX7 (0.37) | TDP1GAAMEN1KMT2AMAPK1 | |
| SCHEMBL6823332 | 0.85 | GAA (0.39) | TDP1HCRTR2GAAMEN1KMT2A | |
| SCHEMBL1222522 | 0.85 | HCRTR2 (0.33) | TDP1HCRTR2GAAMEN1KMT2A | |
| SCHEMBL437782 | 0.83 | TDP1 (0.33) | TDP1HCRTR2 | |
| SCHEMBL24071256 | 0.81 | CTSL (0.35) | TDP1HCRTR2GAAMEN1KMT2A | |
| SCHEMBL29674156 | 0.81 | TDP1 (0.35) | TDP1HCRTR2GAAMEN1KMT2A | |
| SCHEMBL565122 | 0.80 | CA12 (0.31) | HCRTR2CA1CA2CA7 | |
| SCHEMBL436763 | 0.80 | APLNR (0.31) | HCRTR2APLNR | |
| SCHEMBL14733194 | 0.80 | SPHK1 (0.38) | TDP1MEN1KMT2AAPLNRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570617-B2 | Use of triazole compound as ghrelin receptor agonist | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2026-03-10 | — | — | US | disclosed |
| US-12398109-B2 | 2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting ASM activity, and use thereof | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2025-08-26 | — | — | US | disclosed |
| CN-120081796-A | Use of triazole compounds as gastric somatostatin receptor agonists | 庆北大学校产学协力团 | 2025-06-03 | — | — | CN | disclosed |
| CN-116669575-B | Use of triazole compounds as gastric somatostatin receptor agonists | 庆北大学校产学协力团 | 2025-04-04 | — | — | CN | disclosed |
| EP-3789380-B1 | 2-AMINO-2-(1,2,3-TRIAZOLE-4-YL)PROPANE-1,3-DIOL DERIVATIVE OF NOVEL COMPOUND FOR DIRECTLY INHIBITING ASM ACTIVITY, AND USE THEREOF | KYUNGPOOK NAT UNIV IND ACADEMIC COOP FOUND (KR) | 2024-12-04 | — | — | EP | disclosed |
| WO-2024175677-A1 | PROBES FOR DISTINCTION OF STERILE AND BACTERIAL INFECTION | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2024-08-29 | — | — | WO | disclosed |
| CN-112351974-B | Novel compound 2-amino-2- (1, 2, 3-triazole-4-yl) -1, 3-propanediol derivative capable of directly inhibiting ASM activity and application thereof | 庆北大学校产学协力团 | 2024-01-26 | — | — | CN | disclosed |
| US-20230339869-A1 | USE OF TRIAZOLE COMPOUND AS GHRELIN RECEPTOR AGONIST | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2023-10-26 | — | — | US | disclosed |
| US-20230339869-A1 | USE OF TRIAZOLE COMPOUND AS GHRELIN RECEPTOR AGONIST | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2023-10-26 | — | — | US | disclosed |
| US-20230339869-A1 | USE OF TRIAZOLE COMPOUND AS GHRELIN RECEPTOR AGONIST | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2023-10-26 | — | — | US | disclosed |
| US-7560477-B2 | Compounds active in sphingosine 1-phosphate signaling | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2009-07-14 | — | — | US | disclosed |
| US-20090137530-A1 | Amine Compound and Use Thereof for Medical Purposes | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
| US-20090137530-A1 | Amine Compound and Use Thereof for Medical Purposes | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
| US-20090137530-A1 | Amine Compound and Use Thereof for Medical Purposes | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-1961734-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-08-27 | — | — | EP | disclosed |
| WO-2008030118-A1 | ACYCLIC AMINE INHIBITORS OF 5'-METHYLTHIOADENOSINE PHOSPHORYLASE AND NUCLEOSIDASE | INDUSTRIAL RESEARCH LIMITED (NZ) | 2008-03-13 | — | — | WO | disclosed |
| WO-2008030119-A1 | ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2008-03-13 | — | — | WO | disclosed |
| US-20070219163-A1 | Compounds Active in Sphingosine 1-Phosphate Signaling | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2007-09-20 | — | — | US | disclosed |
| US-7241790-B2 | Compounds active in spinigosine 1-phosphate signaling | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-20070088002-A1 | Orally available sphingosine 1-phosphate receptor agonists and antagonists | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137530-A1 | Amine Compound and Use Thereof for Medical Purposes | HRH3, HRH2, HRH4 | TDP1 3754/4885HCRTR2 96/4885GAA 3585/4885 |
| US-20070088002-A1 | Orally available sphingosine 1-phosphate receptor agonists and antagonists | S1PR3, S1PR1, S1PR5 | TDP1 2387/4885HCRTR2 127/4885GAA 4375/4885 |
| US-12570617-B2 | Use of triazole compound as ghrelin receptor agonist | GIPR, GLP1R, GCGR | TDP1 4547/4885HCRTR2 436/4885GAA 3251/4885 |
| US-20230339869-A1 | USE OF TRIAZOLE COMPOUND AS GHRELIN RECEPTOR AGONIST | GIPR, GPR119, GLP1R | TDP1 4580/4885HCRTR2 124/4885GAA 1471/4885 |
| US-12398109-B2 | 2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting ASM activity, and use thereof | CHRNB2, ACHE, SMPD2 | TDP1 166/4885HCRTR2 500/4885GAA 409/4885 |
| US-20070219163-A1 | Compounds Active in Sphingosine 1-Phosphate Signaling | S1PR3, S1PR1, S1PR5 | TDP1 2226/4885HCRTR2 54/4885GAA 4621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.