Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539856 | 0.86 | ABCG2 (0.37) | RAB9APOLBMAPK1MAPT | |
| SCHEMBL7968467 | 0.84 | MAPT (0.39) | NPC1RAB9APOLBMAPK1ALDH1A1 | |
| SCHEMBL7956413 | 0.84 | CFTR (0.39) | ALDH1A1MAPTSMN1; SMN2MEN1LMNA | |
| SCHEMBL7971836 | 0.79 | APP (0.49) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL6932670 | 0.77 | MDM2 (0.38) | NPC1RAB9AMDM2POLBALDH1A1 | |
| SCHEMBL7966269 | 0.77 | LMNA (0.40) | NPC1RAB9AMDM2POLBALDH1A1 | |
| SCHEMBL6932932 | 0.76 | MDM2 (0.38) | NPC1RAB9AMDM2ALDH1A1MAPT | |
| SCHEMBL6026229 | 0.74 | ADK (0.39) | POLBMAPK1ALDH1A1MAPTAR | |
| SCHEMBL6932601 | 0.74 | CFTR (0.43) | POLBALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7971494 | 0.74 | ALDH1A1 (0.33) | MDM2MAPK1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |