Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973956 | 0.92 | CYP11B1 (0.42) | SMN1; SMN2NOTUMCYP11B1CYP11B2KDM4E | |
| SCHEMBL7958185 | 0.91 | CYP11B1 (0.39) | CYP11B1CYP11B2 | |
| SCHEMBL7973955 | 0.86 | PDE5A (0.32) | SMN1; SMN2CYP11B1CYP11B2KDM4EALDH1A1 | |
| SCHEMBL7971638 | 0.66 | FNTA (0.47) | FABP4CYP11B1CYP11B2MAPT | |
| SCHEMBL7970889 | 0.66 | TAAR1 (0.47) | — | |
| SCHEMBL7969216 | 0.66 | BRS3 (0.37) | SMN1; SMN2TP53KDM4EALDH1A1HSD17B10 | |
| SCHEMBL10789640 | 0.66 | CYP3A4 (0.47) | SMN1; SMN2CYP11B1CYP11B2POLBMEN1 | |
| SCHEMBL729589 | 0.64 | ALDH1A1 (0.57) | SMN1; SMN2TP53KDM4EALDH1A1HSD17B10 | |
| SCHEMBL19787909 | 0.64 | MAPT (0.60) | SMN1; SMN2TP53NOTUMKDM4EALDH1A1 | |
| SCHEMBL11308650 | 0.63 | ALDH1A1 (0.52) | SMN1; SMN2TP53KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |