Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 7/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973956 | 0.91 | CYP11B1 (0.42) | CYP11B1CYP11B2FNTAFNTBKDM4C | |
| SCHEMBL7969213 | 0.91 | FABP4 (0.37) | CYP11B1CYP11B2 | |
| SCHEMBL7973955 | 0.89 | PDE5A (0.32) | CYP11B1CYP11B2IDO1AGTR1AGTR2 | |
| SCHEMBL7984767 | 0.72 | KDM4C (0.36) | CYP11B1CYP11B2IDO1CHRM1FNTA | |
| SCHEMBL27353030 | 0.70 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1CHRM1CYP19A1 | |
| SCHEMBL683433 | 0.66 | AGTR1 (0.54) | CYP11B1CYP11B2AGTR1AGTR2 | |
| SCHEMBL4793837 | 0.66 | CYP11B1 (0.58) | CYP11B1CYP11B2CHRM1AGTR1AGTR2 | |
| SCHEMBL7958189 | 0.65 | FNTA (0.42) | FNTAHNF4AKDM4CKDM5BPGGT1B | |
| SCHEMBL729589 | 0.64 | ALDH1A1 (0.57) | MMP2HNF4A | |
| SCHEMBL2551563 | 0.63 | AGTR1 (0.47) | FNTAFNTBAGTR1AGTR2PGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |