Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 3/20 | 0.46 |
| ▸ | F10 | P00742 | 3/20 | 0.46 |
| ▸ | F11 | P03951 | 3/20 | 0.46 |
| ▸ | F7 | P08709 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972949 | 0.91 | F9 (0.46) | F9F10F11F7MITF | |
| SCHEMBL7969287 | 0.87 | F9 (0.46) | F9F10F11F7MITF | |
| SCHEMBL7975112 | 0.81 | F9 (0.47) | F9F10F11F7 | |
| SCHEMBL16258933 | 0.81 | F9 (0.47) | F9F10F11F7 | |
| SCHEMBL7969289 | 0.81 | F9 (0.48) | F9F10F11F7 | |
| SCHEMBL7977818 | 0.78 | F9 (0.48) | F9F10F11F7DHODH | |
| SCHEMBL7973330 | 0.77 | F9 (0.44) | F9F10F11F7PARP1 | |
| SCHEMBL7980064 | 0.74 | GSK3B (0.49) | F9F10F11F7PARP1 | |
| SCHEMBL7969756 | 0.74 | F10 (0.42) | F9F10F11F7 | |
| SCHEMBL7973518 | 0.73 | F9 (0.43) | F9F10F11F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |