Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 9/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PRF1 | P14222 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960905 | 0.91 | F9 (0.46) | F9F10F11F7PARP1 | |
| SCHEMBL7969287 | 0.87 | F9 (0.46) | F9F10F11F7TLR8 | |
| SCHEMBL7960261 | 0.82 | PARP1 (0.40) | F9F10F11TLR8TLR7 | |
| SCHEMBL7975112 | 0.81 | F9 (0.47) | F9F10F11F7CHEK2 | |
| SCHEMBL16258933 | 0.81 | F9 (0.47) | F9F10F11F7CHEK2 | |
| SCHEMBL7969289 | 0.81 | F9 (0.48) | F9F10F11F7 | |
| SCHEMBL7977818 | 0.78 | F9 (0.48) | F9F10F11F7DHODH | |
| SCHEMBL7973330 | 0.77 | F9 (0.44) | F9F10F11F7PARP1 | |
| SCHEMBL7980064 | 0.76 | GSK3B (0.49) | F9F10F11F7PARP1 | |
| SCHEMBL7959321 | 0.75 | F10 (0.40) | F9F10F11F7PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |