SCHEMBL7976230

SCHEMBL7976230

O=C(OCc1ccccc1)C(CCCCOS(=O)(=O)c1ccccc1)OS(=O)(=O)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 1/20 0.38
MMP2 P08253 3/20 0.38
MMP9 P14780 3/20 0.38
ALDH1A1 P00352 4/20 0.37
CDC25B P30305 1/20 0.37
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
MAPK1 P28482 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
ELANE P08246 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A3 Q01959 1/20 0.36
KMT2A Q03164 1/20 0.36
CASP1 P29466 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
LMNA P02545 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7969990 0.96 ALDH1A1 (0.38) CTRCMMP2MMP9ALDH1A1CDC25B
SCHEMBL7969820 0.92 LMNA (0.46) CTRCCA1CA2ELANELMNA
SCHEMBL7068104 0.91 ALDH1A1 (0.40) ALDH1A1CDC25BCA12CA1CA2
SCHEMBL7971433 0.89 FKBP1A (0.38) ALDH1A1CA1CA2CA9MAPK1
SCHEMBL7975992 0.89 LMNA (0.47) CTRCCA1CA2ELANELMNA
SCHEMBL7969622 0.86 TDP1 (0.42) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL7973451 0.85 CA1 (0.38) ALDH1A1CA1CA2CA9MAPK1
SCHEMBL7972944 0.85 KMT2A (0.39) CA12CA2CA9MAPK1KMT2A
SCHEMBL7971318 0.84 CTRC (0.40) CTRCALDH1A1MAPK1L3MBTL1TDP1
SCHEMBL7959874 0.84 MAPT (0.39) CTRCL3MBTL1TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6172234-B1 Optically active cyclic amino acid ester derivatives and processes for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-01-09 US disclosed
EP-0976729-A1 Optically active cyclic amino acid ester derivatives and processes for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-02 EP disclosed